Study of the Effect of General Anesthesia on Myocardium Function in Non-Cardiac Surgery (Laparoscopic Cholecys-tectomy)

Abstract

Cardiac complications are a frequent concern following major non-cardiac surgical procedures. Globally, approximately 4% of the population undergoes surgery each year, with nearly 30% of these classified as major operations performed in individuals presenting with at least one cardiovascular risk factor. This study was designed to evaluate the impact of general anesthesia on myocardial function during non-cardiac surgery. The investigation was conducted at Tripoli Medical Hospital in collaboration with several private clinics and involved a cohort of 60 patients aged between 30 and 70 years, all of whom had a Revised Goldman Cardiac Risk Index of 0, as per the Lee criteria. Patients were admitted to the operating room without premedication. Baseline monitoring included vital parameters such as arterial blood pressure, heart rate, and oxygen saturation. Two peripheral venous catheters were inserted, one for fluid administration and the other for blood sampling. Participants were randomly divided into two equal groups (Group A and Group B), each comprising 30 patients. There were no statistically significant differences between the groups in terms of demographic characteristics, hemodynamic parameters, or serum cardiac troponin I (cTnI) levels. Notably, cTnI concentrations remained within baseline values across all samples collected. The findings of this study suggest that, under the conditions examined, general anesthesia does not pose a measurable risk to myocardial function in patients undergoing non-cardiac surgery. Nevertheless, careful elimination of cardiovascular risk factors and preservation of cardiac hemodynamic stability remain essential components of perioperative care.