First Extraction of Onopordum Cyrenaicum Maire and Weiller and It's Antibacterial Activity

المؤلفون

  • Khamis A. Atayalla Department of Chemistry, Faculty of Science, Sebha University, Sebha, Libya
  • Mohamed A. Ackacha Department of Chemistry, Faculty of Science, Sebha University, Sebha, Libya

الكلمات المفتاحية:

Onopordum cyrenaicum، phytochemicals، inhibition zone، antibacterial properties

الملخص

Herbal medicines and their derivatives are best available from raw plant extracts. Onopordum cyrenaicum Maire & Weiller: medicinal plant endemic to Libya, Asteraceae species in Onopordum genus. The phytochemical profiling and antibacterial activity of this plant are investigated for the first time in this study. Slight modification of maceration technique was used to extract bioactive components step by step using 3 different solvents (petroleum ether, chloroform and ethanol). We have performed the phytochemical analysis for the detection of various components, which were terpenoids, tannins, glycosides, flavonoids, saponins and alkaloids. Of note, the ethanol extract possessed the highest antibacterial action when compared to other extracts, yielding inhibition zones of 28 mm (S. aureus), 22 mm (MRSA), and 30 mm (S. epidermidis); while being 6.25, 50, and 3.75 mg/ml as the minimum inhibitory concentrations (MIC) respectively.

Dimensions

منشور

2025-02-13

كيفية الاقتباس

Khamis A. Atayalla, & Mohamed A. Ackacha. (2025). First Extraction of Onopordum Cyrenaicum Maire and Weiller and It’s Antibacterial Activity. مجلة شمال إفريقيا للنشر العلمي (NAJSP), 3(1), 91–96. استرجع في من https://najsp.com/index.php/home/article/view/386

إصدار

القسم

محور العلوم التطبيقية والطبيعية