Evaluate of Leucocyte Count, Erythrocyte Sedimentation Rate and C-reactive Protein Levels in Patients with Acute and Chronic Inflammation in Al ajaylat City – Libya

الملخص

Inflammatory and infectious diseases are considered as the major causes of sickness and death. Thus, identification of inflammatory diseases markers is a significant tool for the disease's diagnosis and their treatment evaluation. C-reactive protein (C-RP), Erythrocytes sedimentation rate (ESR) and total leucocytes count (TLC) measure the markers that represent the inflammation level in the body at the time of the test and considered as conventional methods of inflammatory diseases preliminary diagnosis. The aim of this study was to evaluate C-RP, ESR and TLC among patients suffer from acute inflammation, chronic inflammation and infection diseases. This study was conducted at Al ajaylat diagnostic laboratories, a sum of 103 blood samples were collected from patients (37 males and 66 females) with different inflammatory and infectious diseases. The samples were tested for C-RP, ESR and TLC. The markers were measured at different stages of diseases course. A questionnaire was used including patient lifestyle, demographic information, preclinical and clinical data, and diagnosis that were collected and analyzed. The percentage of samples that showed abnormal ESR were (89.32%), and C-RP was high in (52.43%) and 24 patients had variations in TLC (23.30%). This study showed that there were no significant differences between ESR and C-RP in both acute and chronic inflammatory conditions. Their levels were useful during treatment follow-up in most acute inflammation. ESR was more value in chronic inflammatory process. Changes in blood cells count were likely to be more prevalent during chronic inflammation. The combination of three tests was more valuable than single test despite their divergence results and significant effects of patient’s gender.